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ORIGINAL ARTICLE
Year : 2013  |  Volume : 106  |  Issue : 2  |  Page : 70-73

Effects of preoperative subconjunctival injection of bevacizumab with primary pterygium surgery


Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Correspondence Address:
Amr Abdel-Fattah
Faculty of Medicine, Ophthalmology Department, The ring road, Suez Canal University, Ismailia
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.7123/01.JEO.0000431541.30326.c9

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Purpose

The aim of this study was to evaluate the preoperative subconjunctival injection of bevacizumab as an adjunctive treatment for primary pterygium surgery.

Design

This was a prospective interventional study.

Patients and methods

Forty eyes of 38 patients were recruited in this study. Three days before pterygium surgery (simple excision using the bare sclera technique), 20 eyes received 2.5 mg/0.1 ml bevacizumab and the other 20 eyes (control group) did not receive any medications. The main outcome measure was recurrence of pterygia and complications during the first 6-month postoperative period.

Results

There were no statistically significant differences with regard to age, sex, or operated eye between the two groups. The pterygia resolved in 14 eyes (70%) of 20 in each group, with a recurrence rate of 30% during the follow-up period of 6 months. There were no statistically significant differences in terms of the improvement in visual acuity, corneal epithelial healing, conjunctival erythema, subconjunctival hemorrhage, lacrimation, or photophobia between the pretreated and control groups.

Conclusion

Subconjunctival injection of bevacizumab before excision has no effect on the recurrence rate of pterygia or on early postoperative complications.



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